Ultrastructural, cytochemical, and membrane surface marker characteristics of the atypical lymphocytes in infectious mononucleosis

Ultrastructural, cytochemical, and membrane surface marker characteristics of the atypical lymphocytes in infectious mononucleosis.

Atypical lymphocytes from nine young adults with acute infectious mononucleosis (IM) were studied for morphologic, ultrastructural, cytochemical, and membrane surface marker characteristics. There was an absolute increase in T lymphocytes in the patients. Atypical lymphocytes accounted for 83%-96% of the lymphocyte population. These lymphocytes contained cytoplasmic inclusions which ranged in s...

The "infectious Mononucleosis Cell". a Cytochemical Study.

iii infectious mononucleosis has been the subject of controversy. It is now generally accepted that they belong to the lymphocytic series 3 although an occasional worker4 holds out for their monocytic origin. Recently, Paegle,#{176} usmg the electron microscope, found that most of the cells in the blood of l) ttients with infectious mononucleosis contained organelles similar to those of the cel...

Atypical infectious mononucleosis in the elderly.

Dna and Rna Synthesis of Circulating Atypical Lymphocytes in Infectious Mononucleosis.

I T IS NOW generally agreed that the atypical mononuclear cells associated with infectious mononucleosis are members of the lymphocyte family,”2 but little is known about physiologic differences that may exist between the abnormal cells and normal lymphocytes. One approach to an understanding of such differences has been the study of nucleic acid synthesis. Using radioautographic technics, Gavo...

Hand-mirror lymphocytes in infectious mononucleosis.

The identification of a morphologically unique lymphocyte in the peripheral blood of patients with infectious mononucleosis (IM) led to additional studies. Examination of Wright-stained smears of EDTA anticoagulated blood obtained from 25 patients with IM at presentation revealed significantly increased (p less than 0.0001) percentages of hand-mirror lymphocytes (HML) (mean 9.2%) compared with ...